HMO strain

6′-Sialyllactose (6′-SL)

Human milk oligosaccharide 6′-SL (6′-Sialyllactose) is the most abundant sialylated HMO in human milk. 

 

 

Health benefits and studies

The specific functional benefits of 6′-SL include reducing the risk of adhesion of harmful bacteria and their proteins.1, 2, 3 3′-SL and 6′-SL in particular support brain development in infants by supplying sialic acid, an essential building block for neurons.4


References

1 Simon et al. “Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides.” Infect Immun.2(1997): 750–757.
2 Amr El-Hawiet, Elena N Kitova, John S Klassen, “Recognition of human milk oligosaccharides by bacterial exotoxins”. Glycobiology, Volume 25, Issue 8, (2015): 845–854.
3 Hester et al. “Human milk oligosaccharides inhibit rotavirus infectivity invitro and in acutely infected piglets.” J. Nutr. 110.7 (2013): 1233−42.
4 Wang B. “Molecular Mechanism Underlying Sialic Acid as an Essential Nutrient for Brain Development and Cognition.” Nutrition, 1.3 (2012): 465S-472S.

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