L. plantarum, PPLP-217

Lifelong healthy development begins in infancy

The period from conception to a child’s second birthday offers a unique window of opportunity to shape lifelong health.1 This period plays a pivotal role in fostering healthy growth, as well as nurturing the development of a healthy gut and the immune system; three areas that are intricately connected and associated with health throughout life.2


Chr. Hansen’s probiotic strain L. plantarum, PPLP-217 

Isolated from the diaper of a healthy infant, the probiotic strain L. plantarum, PPLP-217 combined with prebiotic fructooligosaccharide (FOS) efficiently colonizes the infant gastrointestinal tract and supports gut health, immune health and healthy growth in infants and toddlers. 



L. plantarum, PPLP-217 may support health in infants and toddlers 

A synbiotic containing the probiotic strain L. plantarum, PPLP-217 showed that it may: 

  • Support a well-balanced microbiome
  • Lower risk of health challenges in infants7 
  • Support healthy growth-for-age in infants and toddlers6, 8

Clinical studies documenting benefits of L. plantarum, PPLP-217 

In four clinical studies of newborns who were followed from birth to between 2-24 months, the synbiotic of L. plantarum, PPLP-217 + FOS, showed the following results: 


Healthy growth

  • 27% higher weight gain at 6 months6
  • 26% fewer low-height-for-age children at 2 years8


Healthy immune system 

  • 35% fewer incidences of respiratory tract discomfort at 2 months7 
  • 80% fewer incidences of loose stools at 2 months
  • 35% fewer markers of resistant bacteria at 1 year8  


Quality and safety are always our priority 

At Chr. Hansen, we maintain full control of all the manufacturing steps in the production of our probiotic strains, resulting in exceptional quality. Our production site is a certified GMP Facility, FSSC22000 certified including ISO22000. 
L. plantarum, PPLP-217 has QPS (Qualified Presumption of Safety) status in the EU, and is GRAS notified in the US. 




Note: Due to a 2020 name reclassification, the probiotic L. plantarum, PPLP-217, whose current name is Lactiplantibacillus plantarum, would have been called Lactobacillus plantarum at the time of these studies. 

1Yao Y et al., Front Immunol. 2021; 12: 708472 
2Wang S et al., FEMS Microbiology Reviews. 2020; 44: 763-781
6Panigrahi P et al., Journal of Pediatric Gastroenterology and Nutrition. 2008; 47(1):45-53 
7Panigrahi P et al., Nature, 2017, 548(7668):407-412 
8Pravash R, 2018, Patent pending WO 2019/069267 A1 

PPLP-217™ is a trademark of Chr. Hansen A/S 
PPLP-217™ may also be referred to as ATCC 202195 



This communication is only intended for business-to-business and health care professionals. This communication is not intended for consumers of final consumer goods. Nothing on this page is meant to be perceived as an approved claim.

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