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3-Fucosyllactose (3-FL)

The human milk oligosaccharide 3-FL (3-Fucosyllactose) is one of the most abundant HMOs in breast milk. Research has shown, that the concentration of 3-FL actually increases in breast milk during the length of the lactation phase.1  

 

 

Health benefits and studies

3-FL is especially known for lowering the risk of gut microbiome imbalance due to harmful bacteria.2, 3 Further, 3-FL has been shown to selectively stimulate helpful bifidobacteria to support overall gut health.4


References

1 Plows, Jasmine F., et al. "Longitudinal Changes in Human Milk Oligosaccharides (HMOs) Over the Course of 24 Months of Lactation." The Journal of Nutrition (2021)..
2 Weichert, Stefan, et al. „Bioengineered 2′-fucosyllactose and 3-fucosyllactose inhibit the adhesion of Pseudomonas aeruginosa and enteric pathogens to human intestinal and respiratory cell lines.“ Nutrition research10 (2013): 831-838.
3 Craft, Kelly M., and Steven D. Townsend. „The human milk glycome as a defense against infectious diseases: rationale, challenges, and opportunities.“ ACS infectious diseases2 (2018): 77-83.
4 Bode, Lars. „Human milk oligosaccharides: prebiotics and beyond.“ Nutrition reviewssuppl_2 (2009): S183-S191.

 

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