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Bifidobacterium animalis subsp. lactis (BB-12®)

Facts about Bifidobacterium animalis subsp. lactis (BB-12®)

  • Identified as Bifidobacterium animalis subsp. lactis
  • Strain deposit number: DSM15954
  • Originates from Chr. Hansen’s collection of dairy cultures
  • BB-12® is a registered trademark of Chr. Hansen A/S
  • Used worldwide since 1985 as an ingredient in food and dietary supplements, with no reported consumer illness or injury
  • Tested in clinical studies in persons ranging from new-born preterm infants to the elderly in doses up to at least 100 billion CFU/day, with no reported serious adverse event

The world’s best documented probiotic Bifidobacterium

Used in food and dietary supplements since 1985, described in more than 3601 scientific publications and backed by more than 1651 clinical studies, Bifidobacterium animalis subsp. lactis (BB-12®) is the world’s best documented probiotic Bifidobacterium.

Bifidobacterium (BB-12®) has received a Generally Recognized As Safe (GRAS) status by the Food and Drug Administration (FDA) in the US. In Europe, Bifidobacterium animalis has been granted Qualified Presumption of Safety (QPS) status since 2007 by the European Food Safety Authority (EFSA) - a status granted on species level.

Clinical studies

The large number of clinical studies and scientific publications indicate that the BB-12® probiotic strain – alone or in combination with other of our probiotic strains – may have beneficial effects regarding the gastrointestinal and immune areas.

Alone, the BB-12® probiotic strain:

  • May reduce the risk of an upset stomach2
  • May enhance the immune response3
  • May reduce respiratory tract infections4
  • May support bowel function5
  • May reduce crying, fussiness and irritability in infants6
  • May alleviate symptoms of skin irritation7

Combined, the BB-12® and LA-5® probiotic strains:

  • May reduce the duration of stomach upset8 
  • May support the re-colonization of the intestinal microbiota9

Nothing on this page is meant to be perceived as an approved claim.

Your opportunities

We offer Bifidobacterium (BB-12®) for dietary supplements, infant formula and fermented milk products. Please contact us for more information about the probiotic strain.

1 As of July 2015
2 Chouraqui et al. 2004; Saavedra et al. 1994)
3 Holscher et al. 2012; Rizzardini et al. 2012; Schiffrin et al. 1997
4 Smith et al. 2013; Taipale et al. 2011
5 Matsumoto et al. 2001; Murakami et al. 2006; Nishida et al. 2004; Pitkälä et al. 2007; Uchida et al. 2005
6 Saavedra et al. 2004
7 Isolauri et al. 2000
8 Chatterjee et al. 2013; de Vrese et al. 2011
9 Nord et al. 1997

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