Facts about Lactobacillus (L. CASEI 431®)
Identified as Lactobacillus paracasei subsp. paracasei
Isolated from infant feces
L. CASEI 431® is a registered trademark of Chr. Hansen A/S
Used worldwide since 1995 as an ingredient in food and food supplements, with no reported consumer illness or injury
Tested in clinical studies from infants to adults, with no reported serious adverse events
Strong clinical documentation package
The L. CASEI 431® probiotic strain has been used in food and dietary supplements since 1995 and is one of the best documented probiotic Lactobacillus strains. It has been described in over 801 scientific publications and more than 201 clinical studies. Most recently, the world’s largest clinical study on the immune effect of probiotics (L. CASEI 431®) in adults was published2.
The US Food and Drug Administration (FDA) has designated the L. CASEI 431® strain as Generally Recognized As Safe (GRAS). In addition, Lactobacillus paracasei has been reviewed and granted New Dietary Ingredient (NDI) status by US FDA. In Europe, Lactobacillus paracasei has been granted Qualified Presumption of Safety (QPS) status since 2007 by the European Food Safety Authority (EFSA) – a status granted on species level.